Job Description
Job Description
Role Analytical Chemistry Team Leader
Location Alderley Park, Cheshire, England
Job Type Permanent
Salary £50,000 - £80,000
Date posted June 2023
Start date ASAP
The Company
Sai Life Sciences is a leading global Contract Research & Development and Manufacturing Organisation (CDMO) that provides integrated drug substance services to the biotechnology and pharmaceutical industries. With recently expanded process development labs in Manchester, UK & Hyderabad, India, and increased commercial manufacturing capacity in Bidar, India, Sai is working with 7 of the top 10 pharma companies globally, as well as many leading smaller biotechs. We work with our clients to accelerate the discovery, development and manufacture of complex small molecules for a healthier tomorrow. With more than 2500 staff globally and ambitious growth plans, our vision is to support our global innovator partners to bring 25 new medicines to life by 2025.
Marking the completion of 20 years since inception in 2019, the company began an organisation-wide initiative to significantly expand and upgrade its R&D and manufacturing facilities, deepen scientific & technological capabilities, strengthen automation and data systems, and above all raise the bar for safety, quality and customer focus. Guided by the insights and feedback from its customers, it committed to investing over US$150M between 2019 and 2023. Part of this investment in 2020 were the new state of the art laboratories in our centre of excellence for process chemistry and analytical development at the Alderley Park Science Park, situated on the outskirts of Manchester. Our overall team currently consists of >60 multi-disciplinary scientists (chemists, analysts and engineers).
Non-GMP manufacture of kg quantities of intermediates and APIs is currently possible within our bespoke Scale- up laboratory facility and a new GMP Kilo-lab facility has been brought online recently capable of kg quantities of GMP API suitable for early phase clinical studies. Developed processes are frequently transferred to Sai’s manufacturing sites in India for further scale-up when required.
This role is a great opportunity to work with an expanding global organisation and work closely with some of the most innovative biotech and pharma companies on their most important programs.
The role will be based in Alderley Park, Cheshire, UK and will require right to work in the UK. Occasional travel, domestic and international to India may be required.
The Role
We are looking for an experienced Scientific Leader who is seeking a new challenge.
- You will join a team that identifies, develops and optimises synthetic routes to APIs, supporting both early and late phase development.
- The candidate would lead a team of analytical chemists and would also be expected to generate and review technical proposals for potential new projects
- Collaborate with and provide expert Analytical advice to Process Chemistry colleagues and clients
- Provide support to analytical instrumentation to a cGMP standard
- Support release of materials to clients through characterisation using a variety of analytical techniques
(e.g. LC, NMR, MS).
- Lead the analytical aspects of a process or route development project, coordinating, planning, problem solving and ensuring delivery of analytical development.
Essential Requirements
- Higher or bachelor’s degree in Analytical Chemistry or related scientific discipline with several years' relevant experience in an Analytical Chemistry laboratory.
- Experience of working in a cGMP environment and analysis and release of material for clinical supply
- Strong scientific track record with both project and line leadership experience.
- Experienced in the design, development and optimisation of analytical methods for novel APIs, intermediates and raw materials, working alongside process chemists and engineers.
- Experienced in regulatory requirements for the development and validation of methods for pharmaceuticals, including the separation of impurities and degradation products in APIs
- In-depth, hands-on expertise and up-to-date knowledge of other analytical methodologies such as techniques for identity or impurity determination.
- Experience in generating specifications and out of specification and atypical result investigations.
- Strong scientific track record and analytical project leadership experience.
- The successful candidate will have a background in Organic Chemistry combined with demonstrated expertise in Analytical Chemistry in support of process development for the manufacture of APIs, intermediates and raw materials, technology transfer and scale-up
- The successful candidate will also have experience of line management and enabling the personal development of a team of scientists.
Key Roles and Responsibilities
- To be part of the analytical chemistry departmental leadership team and contribute to departmental objective setting and continuous improvement.
- Line management and personal development responsibility for a team of analytical chemists.
- Responsible for the scientific output of the analytical chemistry team and their contribution to customer projects.
- Work within multi-functional project teams operating to tight deadlines, working collaboratively with other departments.
- Lead the analytical aspects of projects both at Alderley and with analysts in India.
- Plan and supervise analytical work to meet project timelines.
- Able to work effectively to GMP Quality Standards.
Key Attributes
- Excellent communication; both verbal and written.
- Ability to build global relationships with colleagues in India and partner organisations
- Ability to influence key stakeholders.
- A team player and proven leader and line manager.
- Conscientious with a can-do attitude and good attention to detail.
- Good project management and supervisory skills.
The Offer
- A competitive Salary and Benefits package including company pension, health and life insurance, 25 days holiday per year and enhanced family leave.
- Work in a state-of-the-art facility on one of the country's leading Biotech & Life Science Parks.
- Flexible working hours and conditions to suit the right candidate.
Next steps
Please send your CV and cover letter to UKrecruitment@sailife.com with details of the role that you are applying for.
As an Equal Opportunities employer, we welcome applications from all suitably qualified persons regardless of their race, sex, disability, religion/belief, sexual orientation or age.
Please note that Sai Life Sciences Ltd is unable to sponsor the visas for any candidates for the above role.
Job Types: Full-time, Permanent
Salary: £50,000.00-£80,000.00 per year
Benefits:
- Bereavement leave
- Casual dress
- Company pension
- Employee discount
- Enhanced maternity leave
- Enhanced paternity leave
- Flexitime
- Free parking
- Life insurance
- On-site gym
- On-site parking
- Private medical insurance
- Referral programme
- Sick pay
- Store discount
Schedule:
- Flexitime
- Monday to Friday
- No weekends
Ability to commute/relocate:
- Macclesfield: reliably commute or plan to relocate before starting work (required)
Education:
Work Location: In person
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