About Healx
Healx is a mission-driven technology company pioneering the next wave of drug discovery to bring novel, effective treatments to rare disease patients around the world. There are 7,000 known rare diseases that affect 400 million people globally, but only 5% of those conditions have an approved treatment. By combining frontier AI technology with deep drug discovery and development expertise, Healx aims to meet this huge unmet need and have unprecedented patient impact for the rare diseases.
Founded in Cambridge, UK, in 2014 by Dr Tim Guilliams (a Biochemical Engineer and tech entrepreneur) and Dr David Brown (co-inventor of Viagra and former Global Head of Drug Discovery at Roche), Healx has raised over $80 million to date and developed a risk-balanced therapeutic portfolio.
Role
Healx has recently established a semi-automated high content imaging workflow within our research laboratory at Chesterford Research Park. We are now looking for an experienced High Content Screening specialist to help us achieve our ambition to develop a multiomics platform to drive the next generation of drug discovery. This role will suit someone with extensive experience of High Content Imaging, who is still looking to lead from the bench but also keen to act as a functional lead on multidisciplinary project teams.
Duties:
Take responsibility for the execution of high content imaging screening in the Healx lab.
Collaborate closely with Tech teams to establish a closed loop between the lab and Healx’s AI-driven drug prediction algorithms.
Provide expert opinion and support in the analysis of large imaging datasets (e.g. cell painting data) and integration of new Machine Learning methods to Healx’s AI platform.
Mentor laboratory staff in the use of high content imaging and automation equipment.
Maintain service contracts relevant to equipment and services required for imaging workflows.
Establish and maintain relationships with external suppliers and contractors. Support development and maintenance of Health and Safety and related policies.Collaborate with Contract Research Organisations and/or academic KOLs where appropriate to complement lab capabilities.
Represent Healx at external meetings and support the generation of publications.
Who we're looking forQualification and Experiences
A degree in a relevant area of biological science.
Extensive experience in assay development and delivering high content imaging screens, including execution of large Crispr and small molecule compound screens.
Deep knowledge of high content imaging platforms.
Experienced end user of automation and liquid handling equipment.
Good knowledge of imaging software and appropriate analysis of large imaging datasets.
Excellent attention to detail and record keeping skills, with experience of using ELNs.
An enthusiasm for improving outcomes by integrating new ideas and technologies into their work.
Proven experience in establishing and maintaining working relationships with internal/external partners.
Reliable, resourceful, and self-motivated.
Desirable but not essential: Prior experience of high-throughput transcriptomics methods (e.g. DRUG-Seq).
Personal Characteristics
Passion: care deeply about Healx’s aims for improving the lives of rare disease patients and how your work will help us
Integrity: live by our company values
Delivers: reliably against agreed objectives
Build great relationships: great communication and collaboration is the key to getting things done
Self-Improver: stay professionally relevant, network, enjoy learning and set high standards for yourself and others
Love feedback: understand that feedback is a vital part of making progress.
Resilience: stay focused and motivated, especially when things get tough.
Adaptable: able to work in an agile and flexible manner within a fast-moving company
Self-Awareness: understand how others perceive you; know your strengths and know your weaknesses
Location
This role is a permanent, full-time role based out of Healx’s laboratory at Chesterford Research Park, Cambridge UK.
Our Values
Care for Rare - Rare disease patients are at the heart of what we do
Grow as individuals - We are learners always seeking to enhance our expertise
Win as a team - We strive to remain inclusive and diverse and we celebrate successes and lessons together
Innovate and deliver - our mission requires rapid innovation and calculated risks that won’t compromise our high standards
What’s on offer
Financial - Competitive salary, stock options, generous employer pension contributions, life insurance,
Personal Development and Growth - Personal learning and development budgets, regular PDP conversations and career support
Health and Wellbeing - Private medical insurance, 25 days holiday + bank holidays, mental health support, yoga and meditation
Family Friendly - Whilst this is a lab-based role, flexible working practices can be considered. We also offer enhanced maternity, paternity and adoption leave, enhanced shared parental leave, miscarriage and fertility leave
How to apply
Please submit your CV and cover letter below or contact polina.turbina@healx.io for more information
For more information about Healx and how we use your data please go to https://healx.io/privacy/