This project will study how transcription factors select and activate their target enhancers. It combines high-throughput and single locus-based approaches in tractable in vitro systems (human embryonic stem cells) with state-of-the-art computational approaches to study the dynamic recruitment of multiple transcription factors at cell type-specific enhancers and define their individual contributions to gene expression.
Results are expected to clarify how specific cell fates are established, addressing a fundamental question in biology and paving the way for efficient cell reprogramming and the generation of specific cell types. The laboratory is part of a larger research group using genomic approaches and is located in a cutting-edge multidisciplinary centre for biomedical research. This position is available from October, and tenable for 36 months.
What you will get in return:
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Fantastic market leading Pension scheme
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Excellent employee health and wellbeing services including an Employee Assistance Programme
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Exceptional starting annual leave entitlement, plus bank holidays
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Additional paid closure over the Christmas period
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Local and national discounts at a range of major retailers
As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.
Our University is positive about flexible working – you can find out more here
Hybrid working arrangements may be considered.
Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies.
Any recruitment enquiries from recruitment agencies should be directed to People.Recruitment@manchester.ac.uk.
Any CV’s submitted by a recruitment agency will be considered a gift.
Enquiries about the vacancy, shortlisting and interviews:
Email:Nicoletta.Bobola@manchester.ac.uk
General enquiries:
Email: People.recruitment@manchester.ac.uk
Technical support:
https://jobseekersupport.jobtrain.co.uk/support/home
This vacancy will close for applications at midnight on the closing date.
Please see the link below for the Further Particulars document which contains the person specification criteria.